Typhoid fever, a preventable infectious disease, remains a significant global health challenge, primarily spread through contaminated food and water. Typhoid Prevention comprehensively examines this persistent threat, detailing the Salmonella Typhi bacterium, the pivotal role of vaccination, and the critical need for improved water and sanitation infrastructure. The book highlights that typhoid fever is not an inevitable consequence but can be significantly reduced through proactive measures. Understanding the lifecycle of Salmonella Typhi is crucial, as is the knowledge that some typhoid vaccines boast high efficacy rates, though logistical challenges persist in resource-limited settings. This book progresses through three major sections: the biology and epidemiology of Salmonella Typhi, vaccine development and delivery, and the importance of clean water and sanitation. It draws on scientific studies, epidemiological data, and case studies to present a holistic view of typhoid prevention. What sets this resource apart is its integration of scientific knowledge with practical strategies, emphasizing community engagement and culturally sensitive approaches. It is a valuable resource for healthcare professionals, policymakers, and anyone interested in global health.