Spherical Nucleic Acid

In the rapidly advancing field of DNA nanotechnology, the integration of spherical nucleic acids (SNAs) holds the promise to revolutionize science and medicine. “Spherical Nucleic Acid,” part of the “DNA Walker” series, offers indepth insights into this breakthrough area of research, with practical applications in diagnostics, drug delivery, and molecular engineering. Designed for professionals, students, and enthusiasts alike, this book serves as an essential guide for anyone interested in the convergence of nanotechnology, molecular biology, and chemistry.

Chapters Brief Overview:

1: Spherical nucleic acid: Introduces the fundamental concept of spherical nucleic acids and their significance in nanotechnology.

2: Peptide nucleic acid: Explores the structure and function of peptide nucleic acids and their role in genetic research.

3: Selfassembly: Discusses the principles of selfassembly in nanostructures and their application to SNAs.

4: Colloidal gold: Focuses on the use of colloidal gold in creating stable and functional DNAbased nanostructures.

5: Nanoparticle: Delves into the variety of nanoparticles used in conjunction with SNAs for therapeutic and diagnostic purposes.

6: Deoxyribozyme: Examines the role of deoxyribozymes in catalyzing biochemical reactions within SNAbased systems.

7: Triplestranded DNA: Investigates the use of triplestranded DNA structures in enhancing the functionality of SNAs.

8: Cellpenetrating peptide: Describes how cellpenetrating peptides facilitate the delivery of SNAs into cells for therapeutic applications.

9: Chad Mirkin: Highlights the contributions of Chad Mirkin, a leading figure in the field of SNAs and DNA nanotechnology.

10: Magnetic nanoparticles: Explores the integration of magnetic nanoparticles with SNAs for targeted drug delivery and imaging.

11: Platinum nanoparticle: Focuses on the use of platinum nanoparticles in the development of advanced SNAbased sensors.

12: Lipidbased nanoparticle: Discusses lipidbased nanoparticles for efficient encapsulation and delivery of SNAs in biological systems.

13: DNA nanotechnology: Provides an overview of DNA nanotechnology and its applications in the broader context of molecular engineering.

14: Nucleic acid secondary structure: Examines the secondary structures of nucleic acids and their importance in SNA functionality.

15: Polyvalent DNA gold nanoparticles: Focuses on the interaction between polyvalent DNA strands and gold nanoparticles in creating robust nanostructures.

16: Core–shell semiconductor nanocrystal: Investigates coreshell semiconductor nanocrystals as novel materials for SNA applications.

17: Niles Pierce: Discusses the work of Niles Pierce and his contributions to the advancement of DNA nanotechnology.

18: Selfassembly of nanoparticles: Covers the process of nanoparticle selfassembly and its role in building complex nanostructures.

19: Polyvalency (chemistry): Explores the concept of polyvalency in chemistry and its impact on the effectiveness of SNAs.

20: Intracellular delivery: Discusses strategies for effective intracellular delivery of SNAs, highlighting therapeutic applications.

21: Guangzhao Mao: Highlights the contributions of Guangzhao Mao in the development of new SNAbased technologies.

“Spherical Nucleic Acid” offers readers a comprehensive look at the current advancements and practical applications of SNAs in the world of molecular science and nanotechnology. From fundamental principles to cuttingedge research, this book provides unparalleled insights into a rapidly evolving field that promises to shape the future of medicine and technology.